Effect-directed analysis and chemical identification of agonists of peroxisome proliferator-activated receptors in white button mushroom
نویسندگان
چکیده
Linoleic acid is the main PPAR ligand in white button mushrooms and may be involved their anti-obesogenic effect.
منابع مشابه
Peroxisome Proliferator-activated Receptors
Peroxisome proliferator-activated receptors (PPARs) are members of the ligand-activated nuclear hormone receptor superfamily of transcription factors that includes receptors for steroids, thyroid hormone, retinoic acid, and vitamin D. Upon activation in the cytoplasm, PPARs heterodimerize with retinoid X receptors (RXR) and form a complex that translocates to the nucleus and regulates gene expr...
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Division of Applied Life Science (BK21 Program), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Gyeongsang National University (GNU), Jinju 660-701, Korea. *E-mail: [email protected] †Bio Computing Major, Korean German Institute of Technology, Seoul 157-033, Korea ‡Division of Quality of Life, Center of Bioanalysis, Korea Research Institute of Standards and Science (KRISS), D...
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Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors of transcription factors composed of three family members: PPARα, PPARβ/δ and PPARγ. This study was aimed to evaluate the role of PPARs in the estradiol production via follicle stimulating hormone (FSH) in the ovine Sertoli cells. At the first step, transcripts of PPARα, PPARβ /δ and PPARγ were evaluated by quantitative r...
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Objective(s): Herbal medicines are promising cancer preventive candidates. It has been shown that Punica granatum L. could inhibit angiogenesis and tumor invasion. In this study, we investigated whether the anti-angiogenic effect of pomegranate peel extract (PPE) is partly attributable to Peroxisome proliferator-activated receptors (PPARs) activation in the Human Umbilical Vein Endothelial Cell...
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ژورنال
عنوان ژورنال: Food & Function
سال: 2021
ISSN: ['2042-6496', '2042-650X']
DOI: https://doi.org/10.1039/d0fo02071k